DPCstruct | MC39405

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)167 ± 34 aa
Standard deviation of domain lengths34.44
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.56
Pfam Score92.52
Assigned Pfam label(s) CL0023- CL0125- PF01576- CL0072- PF00773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S7PTQ6 326-509 None
A0A0L8IIK8 340-490 None
A0A0L7L237 4-100 None
A0A6A5PIA4 21-159 None
A0A3Q1C8R6 36-174 None
A0A146L935 325-482 None
A0A182T607 412-602 None
J9LWT4 179-381 None
F4S586 86-257 None
S7P3W7 71-224 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.