DPCstruct | MC39405

Metacluster Properties and Pfam Annotations

Number of structural domains350
Mean domain length (aa)167 ± 34 aa
Standard deviation of domain lengths34.44
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score79.38
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)31.56
Pfam Score92.52
Assigned Pfam label(s) CL0023- CL0125- PF01576- CL0072- PF00773

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B4IDW0 56-201 RARQDLGSSGVEDMTLLDDLHEASLLWNLRLRYDKGLIYTFAGSILIAVNPYKMFPDAYGLEVAKQYAGRPLGSLPPHLFAIGAAAH…
A0A6E8WCN1 9-118 GVPDMTCISDIDENGINRNLKVRYERDQIYTYTGSILIAVNPYKEIDCYTQEYVAKYHGQKLGLLEPHVFAMAEAAYRNIRDNNTNQ…
A0A6I9YH74 372-557 None
A0A6P8I7R0 6-168 None
A0A7S2XMM1 357-502 None
A0A1B0BJE4 12-144 None
F4Q2M8 448-598 None
A0A811MXY5 2-141 None
A0A446JU38 130-328 None
A0A7R9PXA8 28-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.