DPCstruct | MC39396

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)187 ± 28 aa
Standard deviation of domain lengths27.87
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score84.30
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)17.76
Pfam Score46.43
Assigned Pfam label(s) PF19425- CL0105- CL0187

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2Z6I832 2-187 LETGDTLTTLFARLGLTDTEALRFLRSSPKTRPFVHPQPGQFVTAGVFEDGRIAFLHLYMEGPHDADSRRVEIRREGTIFTASVEPF…
A0A0B8Q309 52-224 PAPTYSYHIKRGDNLSVVFSRLGFAYSDLTKIMEEDLNHLALDTLKPGNTLKFWADDETGKLAKMELEFNPADRVQYTRTDDDTFTF…
A0A2V7KLY3 6-182 None
A0A842JAF4 3-192 None
A0A4Y9EME4 123-335 None
A0A377D5M5 1-145 None
A0A3D5Y1F3 330-526 None
A0A2G1YUN4 36-223 None
A0A2E2EJZ9 67-264 None
A0A1E3VXH9 7-225 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.