DPCstruct | MC39276

Metacluster Properties and Pfam Annotations

Number of structural domains421
Mean domain length (aa)168 ± 26 aa
Standard deviation of domain lengths26.27
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score86.31
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.62
Mean intra-cluster local Distance Difference Test score0.57
Mean intra-cluster sequence similarity (%)13.65
Pfam Score99.22
Assigned Pfam label(s) CL0044- CL0061- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J4KXX2 131-293 TTAGAGDHHDGRGTMGTSATSDSAALLAELNDLLQLDRDAVQAYTLAEQGLESEEYKAAIRRFRGDHERHIRELERLITARGGTPAS…
A0A316SVC7 15-163 VAKVLDELNVALSEEWLAFYQYWVGALVVKGAMRADVQGEFEEHAMEEFAHAKLLADRIIELEGVPVIDPKEWFNLAKCAYLPPTDF…
A0A509EAS1 2-173 None
A0A0D2PAQ8 30-222 None
A0A7M5VFX4 47-192 None
A0A1R4FHV6 1-145 None
A0A1I3UUS7 1-151 None
A0A6P1TKK7 22-160 None
F1VVE5 2-138 None
A0A254TFQ7 28-188 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.