DPCstruct | MC39225

Metacluster Properties and Pfam Annotations

Number of structural domains541
Mean domain length (aa)99 ± 16 aa
Standard deviation of domain lengths15.64
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score83.83
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.01
Pfam Score96.97
Assigned Pfam label(s) CL0023- CL0136- CL0057

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6B1DIC9 180-294 EPAATGLWGTVVWAVDASGKAPAYEYFRDLDDKDAAKMQALFNRLARDGFIKNDEKFKKLYDRNLREFKSFQLRFLGNYTKGRQFLV…
A0A2V8ZUN4 17-115 QAHRQPAFELRYTPDAAADIKALDGSVRNQLRKVLEKKLAIDPEGYGLPLRGSLAGYWKHQFGNHRVVYRIYSQHHVVVVCSVGVRK…
A0A2S2CRA3 1-109 None
A0A1V5XB93 2-114 None
A0A3D1R8V7 76-191 None
A0A0G1XNH9 1-88 None
A0A522ZXI4 9-138 None
A0A7I6XSB9 2-116 None
A0A7H1N5U0 5-101 None
A0A7V2PTV4 5-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.