DPCstruct | MC39145

Metacluster Properties and Pfam Annotations

Number of structural domains424
Mean domain length (aa)351 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.83
Pfam Score60.04
Assigned Pfam label(s) PF02397- CL0142- PF19896- PF15864- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A357IRC5 11-486 None
K2DJI6 56-448 None
A0A7C3NA77 12-377 None
A0A6H2EJ28 56-454 None
A0A7X9G5A8 10-262 None
A0A2M7AKJ6 70-488 None
A0A6B5P6H6 16-277 None
A0A5C7W4E8 15-480 None
A0A2E8H5J8 626-1030 None
A0A2G6C1K1 43-468 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.