DPCstruct | MC39145

Metacluster Properties and Pfam Annotations

Number of structural domains424
Mean domain length (aa)351 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.83
Pfam Score60.04
Assigned Pfam label(s) PF02397- CL0142- PF19896- PF15864- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7R8VZK8 635-975 None
A0A368URU4 2-371 None
A0A136MI40 20-461 None
A0A2H0SYN2 16-525 None
V7I4P2 33-392 None
A0A661W4V7 119-482 None
A0A0R2HB47 6-395 None
A0A317UAN6 7-397 None
A0A7C1PRB4 1-232 None
A0A3S4TYR6 5-272 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.