DPCstruct | MC39145

Metacluster Properties and Pfam Annotations

Number of structural domains424
Mean domain length (aa)351 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.83
Pfam Score60.04
Assigned Pfam label(s) PF02397- CL0142- PF19896- PF15864- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E1AGE6 27-428 None
A0A2U8HMA4 18-380 None
A0A3M1NBC8 32-387 None
A0A6P0UN23 9-318 None
A0A136KSC4 8-309 None
U1PLK5 33-397 None
A0A401LYE4 16-303 None
E3R258 36-280 None
A0A7Y2DAF4 27-391 None
W5XRV8 50-432 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.