DPCstruct | MC39145

Metacluster Properties and Pfam Annotations

Number of structural domains424
Mean domain length (aa)351 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.83
Pfam Score60.04
Assigned Pfam label(s) PF02397- CL0142- PF19896- PF15864- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q7MVI3 71-494 None
A0A1Y4DKD4 22-436 None
A0A0F9W8P2 43-384 None
C5ATW4 21-447 None
A0A060DS59 657-975 None
A5Z6P6 22-359 None
A0A2N5ZVG1 18-364 None
A0A2E7F836 7-363 None
A0A661UBB5 259-688 None
A0A847B3W8 9-276 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.