DPCstruct | MC39145

Metacluster Properties and Pfam Annotations

Number of structural domains424
Mean domain length (aa)351 ± 81 aa
Standard deviation of domain lengths80.87
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score82.36
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.47
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)14.83
Pfam Score60.04
Assigned Pfam label(s) PF02397- CL0142- PF19896- PF15864- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W1FZI5 3-224 None
A0A257UVB1 97-287 None
A0A0T0PUQ0 58-316 None
A0A1D7ZNT6 9-399 None
A0A2N2SIA8 331-736 None
A0A3E0NXQ4 257-631 None
A0A535QSI7 80-344 None
A0A538C1U1 404-977 None
A0A4P5TST3 5-207 None
A0A2V7BJ69 438-831 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.