DPCstruct | MC39120

Metacluster Properties and Pfam Annotations

Number of structural domains2375
Mean domain length (aa)181 ± 37 aa
Standard deviation of domain lengths36.81
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score79.79
Mean fraction of residues predicted as intrinsically disordered0.31
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.38
Mean intra-cluster sequence similarity (%)10.55
Pfam Score22.26
Assigned Pfam label(s) CL0609- PF20127- PF12502- PF18443- PF14285

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A370H0Y2 1-127 MPIAFETGGLQQLDPSTWGNPATGDLVTLAYVDAVPDLPVPLEDIDALRRRLTELQSEFGCLIEAHVLTVAGQPALLRLEKFPLPDR…
A0A7X6CPI2 31-206 GAGIAIAIALGALTFQHFSKTPVENFLTYQSSEHQFAMKYPERWEKQELQNPLIADVLVFTAPKKNSADAYQEQMIVRIEDLPRPMS…
A0A5F2BNI7 12-152 None
A0A3B0CBD1 21-161 None
A0A6L5XRA3 211-399 None
G8S338 831-1005 None
A0A4R3YU57 2-193 None
A0A1V4URE5 37-217 None
A0A518I4G5 2-225 None
E6N3U8 1-168 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.