DPCstruct | MC39078

Metacluster Properties and Pfam Annotations

Number of structural domains92
Mean domain length (aa)128 ± 22 aa
Standard deviation of domain lengths21.55
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score83.54
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.68
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)23.66
Pfam Score87.63
Assigned Pfam label(s) CL0193- PF14330- PF07287

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A446CR64 9-144 PPPPPRPAPDATMAEAAPSTWREPANAVTVPLIRLAWARSGDKGNTSNIGVIARKPEWLELLRSQLTPDRVAQYLAHLVRGPVARYE…
A0A522MH22 2-106 ATALLGRLADGRSGDKGEASNVGLVARNERVYAWLRENLTAEAVRRLLPGIARGPVERYEVPNILALNFILHDSLGGGGTASLLTDA…
W7MMQ4 100-230 None
R1GRK3 221-315 None
A0A100J341 419-561 None
A0A7J6LTW1 436-588 None
A0A1M3T0V4 216-337 None
A0A1J9RNI6 2-202 None
A0A7D7VGT2 2-103 None
A0A438NB83 816-960 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.