DPCstruct | MC39005

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)137 ± 17 aa
Standard deviation of domain lengths17.42
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.37
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)27.19
Pfam Score100.00
Assigned Pfam label(s) PF09232

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A454Y2B5 24-133 KIEAVATKCCPKAAFQCCYDAIDFNQRLSCVDILERKRQETIECIQSELHGENDTMTAGIQHIGCCEAFKDDRTDPRSLCYETCKRM…
A0A0C2FXP6 17-143 HPTHTLLGTIIIASIVVADVKIDSRQISSRCCPQSRRKCCEEVIEKRQPLNCSMPLHELIASSDCIQKEMFGKKSLELARIEDVECC…
A0A7E4W9S5 49-219 None
A0A0N4ZZZ0 1-143 None
H3E5Z9 25-134 None
A0A7E4URD4 1-154 None
A0A0K0G2T4 38-183 None
H3FIN9 10-145 None
H3EIN2 8-154 None
A0A1I7SX45 1-131 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.