DPCstruct | MC38928

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)114 ± 11 aa
Standard deviation of domain lengths11.23
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score88.42
Mean fraction of residues predicted as intrinsically disordered0.32
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)32.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0Q4MRZ0 223-316 LVPKGQLTFDAEGNDIESSPWFSRRVHWPGGVSGITIGRGYDLGQNNSSNNELTEVGVDENLKSWLVGSQSMSGATASTRLNGAPTS…
A0A4R3VHL2 1-115 MLRVPQGQITFDGEGDDSPNSPYFSRVIHWPGNPKSGVTLGRGYDMGGRTKGEVYSDMLRIGIGSEKASLIAMGASLKGAAAAIFVK…
A0A1I3LN83 266-382 None
A0A6S7IGV7 314-406 None
A0A521H295 538-663 None
A0A1H1LQD9 745-864 None
A0A0C9NB98 5-92 None
A0A519FXE3 50-163 None
A0A1C4CVR3 16-126 None
A0A3R8T9C0 278-404 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.