DPCstruct | MC38897

Metacluster Properties and Pfam Annotations

Number of structural domains34
Mean domain length (aa)76 ± 8 aa
Standard deviation of domain lengths8.20
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score82.93
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)31.84
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V5WW48 2-68 KEMELYCATHPRSPAAVRRPRLSIRGRTFVALLGPAIEEGIAGFGDSVQAALRAFDAQYSRSLTPPA
A0A7Z2LCR7 4-89 QESAYASNIFAMQVTQTATDINYAYTRPSTVFKPALSVDGNQWCALYGTDLQSGVAGFGDTPEKAMQDFDNNWNKPLRNSPSGIAL
A0A2V6ECY2 2-67 None
A0A5C7QJL3 80-152 None
A0A2V5WU88 6-79 None
A0A2V5ZPV2 13-83 None
A0A4R7WKB7 3-77 None
A0A0F9U8Y1 2-79 None
A0A7Y4QDT9 83-181 None
A0A2V5VDJ2 2-74 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.