DPCstruct | MC38852

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)388 ± 77 aa
Standard deviation of domain lengths77.22
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score74.38
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.47
Mean intra-cluster sequence similarity (%)14.00
Pfam Score19.44
Assigned Pfam label(s) PF09660- PF18982- CL0123- PF11855- PF17192

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A379AJ37 1-267 MSEFSQTVPELVSWARKNDFSLALPVERLAFLLAIATLNGERMDGEMSEGDLIDAFRHVSKAFEQTHETVLVRANNAINDMVRQRLL…
A0A2T2XDS2 16-384 LAAPNRRLYARAMVVRDCYRREMKFVRSDLVSYFLNDLQPDLLQQVEPEDDAGELRNLSDRAHLLVRRLIETGWLVTDVDDQTLEET…
A0A7J5BNZ3 73-633 None
L1KUW1 2-346 None
A0A7W5FKI5 146-547 None
A0A221W8M4 72-553 None
A0A2T4I8C8 1-421 None
A0A0R1TPG9 1-429 None
A0A2W6VGV3 69-551 None
A0A1B8YMX7 18-314 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.