DPCstruct | MC38819

Metacluster Properties and Pfam Annotations

Number of structural domains249
Mean domain length (aa)152 ± 21 aa
Standard deviation of domain lengths21.42
Length coefficient of variation0.14
Mean AlphaFold2 pLDDT confidence score80.26
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.61
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)19.99
Pfam Score98.57
Assigned Pfam label(s) CL0023- PF05157

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2W5ABS4 7-133 QVALARILEQRGLADMAAIDAAAAGGERIAVALVRSGRVEAQAMAEAVAEATGAALVEPAAPVETANIARSFLADRLAAPLGLEEGR…
E3FU05 11-176 FRKKRLGEILLDAALLSETQLRTALAEQRKWGGKLGHTLVQMGFVDENSMVHALSRQLQIPSVDLAQVAPPAHVFQLFPAALAERYT…
A0A377F9C2 230-333 None
A0A1G1K2A7 143-281 None
A0A5E9G2W2 2-150 None
A0A7V4LZW9 53-215 None
A0A847E6X7 117-257 None
A0A3A4NTV3 1-166 None
A0A076HJN7 116-264 None
Q5SLC9 158-303 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.