DPCstruct | MC38790

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)198 ± 21 aa
Standard deviation of domain lengths21.35
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score90.67
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.63
Mean intra-cluster sequence similarity (%)22.84
Pfam Score100.00
Assigned Pfam label(s) CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7H4MDW7 19-213 QISPAPAVKRVALLGEEYVGMRPAMAVKEGDRVKKGQILFEDKKTPGVYFTAPASGVVSAIHRGERRVLQSVVIDIEGNDAVAFTRY…
A0A2I1M536 3-189 KFNLRMGIGAPASPIVKDGDEVKRGQKIADFDPEQLSVPIYSSVNGKVKEVTDEAIYIEKTDDNKEYLKIDKKDNLADVAREAGIIG…
A0A845SK44 25-229 None
A0A378VTZ2 1-189 None
D4J362 9-235 None
A0A2T7B5M4 32-244 None
A0A110B540 212-426 None
R5MBE4 21-180 None
A0A1I0BL16 591-823 None
A0A7V4NJN4 246-453 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.