DPCstruct | MC3873

Metacluster Properties and Pfam Annotations

Number of structural domains36
Mean domain length (aa)200 ± 33 aa
Standard deviation of domain lengths33.12
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score79.55
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)31.36
Pfam Score95.65
Assigned Pfam label(s) CL0274- CL0705- PF09788

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J2XQ22 28-206 AQRELIDSGKVSRHPISSSDDGQWSEGLISAARLVAAATHSLVESANALVQGLGSEDKLIAAAKQVASSTAHLLVACKVKAEGDTDA…
V9IHW2 1-131 MVAAATHSLVESANALVQGVSSEEKLISSAKQVASSTAQLLVACKVKADPDSDSTKRLQAAGNAVKRATDNLVRAAQQAIQQEEDRS…
E9HPF1 97-299 None
A0A0L7QMW8 214-408 None
A0A5K4F0V3 512-716 None
A0A369S3A3 754-1007 None
A0A834BCH2 1-133 None
A0A0K0EJV8 2388-2590 None
M2REV3 474-698 None
B0ETT5 74-300 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.