DPCstruct | MC3871

Metacluster Properties and Pfam Annotations

Number of structural domains10
Mean domain length (aa)225 ± 25 aa
Standard deviation of domain lengths24.52
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score71.66
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)24.37
Pfam Score100.00
Assigned Pfam label(s) PF12955

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A427Y8B6 216-421 TKAAAALGHELSCLTALAESIPWVDKLRHSTKWDAITISGLRQVPHGSEEWEMGRKGVQAGLEAVNDHPQLPPLLVIILPSSHKTLS…
A0A1M2VVQ1 1-247 MDRAHHVYSYVYEAQEHAFDKPKRQLDAFSVPASGAMTAVGELEAFMDFLDNKELPVDRFGAFDLSRLEDLRETFGKDSDQYRTAIQ…
A0A4P9X698 272-514 None
A0A507DE36 205-378 None
A0A146IE08 587-814 None
A0A3N4I5K5 3-238 None
M5E6Y1 152-387 None
A0A0C3NN74 130-375 None
A0A1Y2FMP8 197-386 None
A0A2N5SFJ6 231-473 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.