DPCstruct | MC38679

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)120 ± 23 aa
Standard deviation of domain lengths22.92
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.41
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.76
Mean intra-cluster sequence similarity (%)45.22
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5N5SR19 115-205 IEEWIVVRRGWLTRGFLDALTLGGPGGAPKPIELQAHDPLRYVGDMLAWIHQALPSEREAAQLLFSKCVDIDASEQVQQTISGVSES…
A0A453IKZ9 43-200 MDMMSVYQEGAYERLCRWVQVECKKPGDTDNPEVSELLKKAVRCLKERPVLFKYCAEEVANMRHHALFRQFISALTRGGPGGLPRPI…
A0A5N5QRZ6 442-544 None
A0A507D9S4 814-921 None
A0A132ACB3 1-147 None
A0A445M3D5 198-303 None
I1BHI8 2-149 None
W2Z4Y4 249-359 None
A0A820ZJK9 1-98 None
A0A6I9YAY3 2-109 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.