DPCstruct | MC38676

Metacluster Properties and Pfam Annotations

Number of structural domains40
Mean domain length (aa)179 ± 51 aa
Standard deviation of domain lengths50.92
Length coefficient of variation0.29
Mean AlphaFold2 pLDDT confidence score83.86
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.77
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)45.70
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
S4PL68 16-160 MNAVVLYVGTQAIAHIRSKGQTPNMTTIAHSAHMDIFQNFTVDFDYEGRYLFLNAIANQLRYPNSHTHYFSCCLLYLFAEANSEAVQ…
A0A812Z2L9 1-146 MYVAAYAVGQQQQQKTQVPLSVAMDIYKYLVTNLDAEARYGLFNIMANQLRYPNNHTHFFSCVLLSLFADADTEFIQEQITRVLLER…
A0A1I7ZGD4 1022-1205 None
A0A813G041 45-232 None
Q7RM05 26-152 None
A0A843WGC8 160-300 None
A0A1I7SA09 4-113 None
A0A3P7MQJ6 258-446 None
A0A5B7CPH8 176-412 None
A0A0R3Q651 95-291 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.