DPCstruct | MC38647

Metacluster Properties and Pfam Annotations

Number of structural domains391
Mean domain length (aa)75 ± 12 aa
Standard deviation of domain lengths12.28
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score77.32
Mean fraction of residues predicted as intrinsically disordered0.41
Mean length-normalized TM-Score0.70
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)28.43
Pfam Score99.27
Assigned Pfam label(s) CL0010- CL0063

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A016U697 4-71 RSSASANATADEEECEAYTVEKILKTRKRGGRREYLIKWEGWPLDQSTWEAESDCDCEEAIKQFYETS
A0A1I7SS50 6-58 KKYPVERILKHKEINGVRWYLIKWEGYPIHRSTWETEDYLDECRETLMDYQLR
A0A2D4FGQ6 1-67 None
G2YYN2 230-308 None
I1CW37 173-243 None
I1CRV9 111-179 None
A0A226EV88 264-343 None
A0A226EKD9 73-160 None
K3WDT0 41-162 None
A0A7R9AA08 193-262 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.