DPCstruct | MC386

Metacluster Properties and Pfam Annotations

Number of structural domains19
Mean domain length (aa)94 ± 8 aa
Standard deviation of domain lengths7.79
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score85.47
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)26.12
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1M3HGG5 4-94 DLNEDQLQLEELMSRISEAGYSAGWMMGLEYELWQILNDGKGSFGRHHVTQEELQQLQFLSEKCGCWVVFDDNTEETAVDLETWKKM…
A3IZ42 11-107 SVNSEASQLLLNMFHELSEDIYCAGWSANIEFYLWEITLETDKNTSTFLRENLKDYQIKELSRLSNLCQGWWVWKDPQGETFVSLDE…
A0A367Q7L1 42-126 None
A0A537MYB9 99-193 None
A0A1C4ITT4 4-106 None
A0A6G8CI44 62-169 None
A0A2T1BZD1 9-97 None
A0A5P8WCA9 110-211 None
A0A1Q8YF43 15-105 None
A0A522P8S1 135-231 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.