DPCstruct | MC38294

Metacluster Properties and Pfam Annotations

Number of structural domains6
Mean domain length (aa)211 ± 28 aa
Standard deviation of domain lengths27.88
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score84.73
Mean fraction of residues predicted as intrinsically disordered0.17
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
R7HIA4 335-538 NVDVIYAGFSEYEKRFKTQHIYNKIDFYKDLLKNGILRPLDPDLAPLEGSIINECVDNKKFQSFTNDNSIIQNISEEYRKVRHNYQK…
L7W086 251-449 EIFQIASEIEAITEGKAPGDMPEATRIASRISYPRYEENPELALICRKYRVREKHFNRCLELEKTAKSRDRLPEVLVDGKEAGYPGY…
A0A3D0Y0G9 55-227 None
A0A2G6C1M1 743-952 None
A0A7X6ADM9 741-952 None
A0A0W1AFZ2 211-476 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.