DPCstruct | MC38248

Metacluster Properties and Pfam Annotations

Number of structural domains377
Mean domain length (aa)184 ± 33 aa
Standard deviation of domain lengths32.50
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score73.65
Mean fraction of residues predicted as intrinsically disordered0.29
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)13.29
Pfam Score95.42
Assigned Pfam label(s) CL0616- PF14774- PF12480- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
G7K0L5 60-218 MTDSETDDSITSEDDFKARPILDANWSGNLRFGDNTINGLMAHLSDLVCPKVWKETELLPDVLSADLLPRSEVWPDSFKKDGPTNKN…
A0A7S2ZYW3 263-385 NRPRWKCRLQKTGKFICNLNAHQIRGPGLGDQGLPYTLVVERRFSLLHLNQFVLPEATMLYFEPVTPEDRPGFEQFIDYLVKRSRAG…
A0A0D2YC79 439-611 None
A0A022QVB7 48-210 None
A0A7N2KU71 526-715 None
A0A2G8LCN3 185-397 None
A0A836J218 100-334 None
A0A4U0VIP5 375-612 None
A0A5N5TK55 1-129 None
A0A7M5TYE7 650-876 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.