DPCstruct | MC38240

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)172 ± 19 aa
Standard deviation of domain lengths19.12
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score72.71
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.54
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)30.65
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
W2IQA3 1-174 MESITLSSADLVLIDVQRSSQLSPELIVLTKFTLDRLATNTYQIYDLDAAKSPQTNEHSLPRHAAHISTLSSNAQICVSRIKGQVAK…
A0A6A3HXG4 309-457 EAVTESLAELARIEVQRSNQVASELIVLLKFAIDRLGADSYNIYDMDALRSPKTNEKTLPRRSIHLSALSAEGQICVARIKGQVEKR…
A0A225WA01 277-474 None
A0A2P4X193 73-263 None
A0A0W8CEW5 154-343 None
D0NGG7 623-765 None
W2LR70 2-197 None
A0A2P4YMQ2 195-393 None
A0A329S4B2 1-153 None
A0A329SA41 1-161 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.