DPCstruct | MC38228

Metacluster Properties and Pfam Annotations

Number of structural domains32
Mean domain length (aa)97 ± 17 aa
Standard deviation of domain lengths17.44
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.61
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.90
Mean intra-cluster local Distance Difference Test score0.86
Mean intra-cluster sequence similarity (%)48.82
Pfam Score100.00
Assigned Pfam label(s) PF05427

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A444T4A5 61-158 YYSFDGSVIREILGKKLSGRTRKDLDDVAEKTGITLRSCRRQFDNVKRIYKQTDDASGSVKLNIQASFLLPPALAQKYATVVFLTSN…
A0A183NLG5 1-121 YYSLDESFLREFVGRRLSNKSRRELSDIAERCELQLRSCKRQFDNLSCVARRTEDLPGPLTDNIKNCFLLPEWLAECYAAVIFIASN…
A0A674GYR3 267-359 None
A0A3P7M0X7 30-117 None
F4WM87 93-177 None
A0A0W8CB53 2-91 None
A0A183KQJ6 60-190 None
A0A1S3I7Q2 4-90 None
A0A0V1BMN1 86-172 None
A0A183SNK3 99-186 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.