DPCstruct | MC38224

Metacluster Properties and Pfam Annotations

Number of structural domains16
Mean domain length (aa)74 ± 3 aa
Standard deviation of domain lengths3.33
Length coefficient of variation0.04
Mean AlphaFold2 pLDDT confidence score94.60
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.96
Mean intra-cluster local Distance Difference Test score0.93
Mean intra-cluster sequence similarity (%)45.39
Pfam Score100.00
Assigned Pfam label(s) CL0052

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183NHK0 1-80 LCRGIVSSLDVTNILKIQGYWASYNLPFIDDIYILSGTKNMAKMHGDWYVHNMTSRAKIFRRDHHKVVDFPSMMSLMRQV
A0A6P7UYR5 116-190 NITKAEDVSAYLQNQKYWGSYNVAFFPAIFNISGQPDMVKKYGNYYSYDMSPRAQIFRREQSKVEDVDTMLRLMR
S4P6H1 37-105 None
A0A0B1SQL5 1-68 None
A0A6G0TWX0 375-449 None
A0A1L8HPY6 102-181 None
J9EKK4 125-198 None
A0A6G0YAL5 64-138 None
A0A2D4KS15 85-159 None
A0A7M3RLT1 163-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.