DPCstruct | MC3814

Metacluster Properties and Pfam Annotations

Number of structural domains1349
Mean domain length (aa)122 ± 18 aa
Standard deviation of domain lengths17.89
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score83.58
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.59
Mean intra-cluster sequence similarity (%)20.00
Pfam Score94.71
Assigned Pfam label(s) CL0689- PF18393- CL0508- PF00691- PF07715

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2E4X6X9 11-119 EVGDRVFFDYDESRFKNEGVETLKRQARFLLNNKDLTVRIEGHCDQRGTREYNLALGERRAFSVKSFLVSLGVEESRISVISYGKEK…
A0A1Q3SEX5 31-152 APTPAKYSVENKEMNAIYHFAFDRSELSEQDMPALNEFATFLHANPSMKAHVDGYTDAQGPYNYNLNLGLRRAEAVAEYLQAKGVPA…
A0A4R4D5T5 30-141 None
A0A7C0Y6G3 16-132 None
A0A537IST2 17-133 None
A0A4R2JQG8 49-175 None
A0A3G2G5L6 307-421 None
A0A7Y3J2Q7 385-514 None
A0A1B0C1Q4 472-602 None
A0A7C0U1U3 248-370 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.