DPCstruct | MC38124

Metacluster Properties and Pfam Annotations

Number of structural domains243
Mean domain length (aa)439 ± 78 aa
Standard deviation of domain lengths78.37
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score87.49
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)16.28
Pfam Score79.38
Assigned Pfam label(s) CL0063- CL0022- CL0123- CL0127- CL0105

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A5C8KKW8 34-488 AGCGVQPLSASPGSTHDDADAARRIEADLRFLADDLLEGRQAGTRGYDLAARYVEARFRAMGLEPGGDAGSYLRAVPMVQGLRIPDG…
A0A825NR48 1-306 HSIKSGTKVFDWIVPDEWNVKEAYIITPEGEKICDFKKHNLHLLNYSEAIDQEIELEELQDHLYSIEEMPDAIPYVTSYYKRRWGFC…
R7UMH0 31-379 None
A0A4P1JYU5 3-358 None
A0A523E0V9 569-1035 None
A0A3P3W2S5 28-467 None
A0A135V988 397-913 None
A0A317V723 418-862 None
A0A446PYH9 38-565 None
R7KMF7 2-415 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.