DPCstruct | MC38118

Metacluster Properties and Pfam Annotations

Number of structural domains270
Mean domain length (aa)281 ± 52 aa
Standard deviation of domain lengths51.67
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score79.67
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.58
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)16.29
Pfam Score89.52
Assigned Pfam label(s) PF18151- PF02204- CL0072

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H2IBN4 18-288 SLEARKEFSDFLVANLSTAMTQEIARSVKNAVGKIVEMRLNLDDMSELVMSYYQYLSERIGGHAFFNTPDCKVKVEDVMDQVEKYIS…
A0A6J1WGV4 2-152 DEKATRLTASIKAITAELKADPSWEGASSALLETLELTVERAAFARLYLHVMFPNGDGDIARDQVLHEHVRRVAGATSAARAGVAAR…
A0A7M7N533 666-940 None
A0A6P8VY83 402-730 None
A0A226F590 561-879 None
A0A226F173 233-524 None
A0A0R3UN12 74-367 None
A0A818ZGY2 124-409 None
A0A5N6Q7N4 346-679 None
B0E5X3 7-237 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.