DPCstruct | MC381

Metacluster Properties and Pfam Annotations

Number of structural domains12
Mean domain length (aa)212 ± 25 aa
Standard deviation of domain lengths24.65
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score89.74
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)24.89
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
B1MNK2 9-208 TDEVDGLIAIGLAHDFWRGQWSTVEEAHIHRPPHRIRRISDGEMFAANIKVTRIMLEEFRSGFDLERVVQRLTEPGQLRVGRWEGTE…
A0A397MTK1 276-468 DTDALVSAAAVGLVADAWREGPLEVIHAADDGPSDGEIFAQSVDLYRRARAALVAARDDGPEVLLAFVAVASDVDLPWAGGSRFALR…
A0A366CSW9 116-323 None
A0A2W6BX50 354-586 None
A0A7G6WWF1 362-567 None
A0A840LUN2 63-241 None
A0A1R0KGI9 2-209 None
A0A4D4LDL3 22-256 None
A0A6B3AZM7 168-398 None
A0A6I8LU84 5-274 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.