DPCstruct | MC38098

Metacluster Properties and Pfam Annotations

Number of structural domains4078
Mean domain length (aa)215 ± 41 aa
Standard deviation of domain lengths40.92
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.17
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)14.41
Pfam Score98.06
Assigned Pfam label(s) CL0205- CL0678- CL0550- CL0113- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2I4BQG3 24-246 KIIHGKEVPKNSMQYMVSIQDKYGFHLCGGFLIREEFVVTAAHCDELESPIHQIFLGSHNLRKNGILKTFDYKCKPPTYENLGLGDD…
Q7M135 18-235 HRDVIRSVAAYSKQGTMWCTGSLVNNSANDKKMYFLTANHCGMTTAAIASSMVVYWNYQNSTCRAPGSSSSGANGDGSLAQSQTGAV…
A0A5B7DEZ9 99-316 None
A0A538QC88 3-168 None
A0A538Q113 372-612 None
A0A5N5TP06 125-301 None
A0A5N5TDE6 284-453 None
A0A6G1IM22 297-562 None
A0A6B1AFY8 126-315 None
A0A2G7GCC3 41-312 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.