DPCstruct | MC38085

Metacluster Properties and Pfam Annotations

Number of structural domains3364
Mean domain length (aa)172 ± 33 aa
Standard deviation of domain lengths32.85
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.82
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.50
Mean intra-cluster sequence similarity (%)16.16
Pfam Score92.50
Assigned Pfam label(s) CL0020- PF16963- CL0304- PF11559- PF11294

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8IJJ6 10-162 LKIRSEIDEEIRRHKTERTVLFTDIVGSTNYFDRFGDTAGLLLIQRHDDFVASAVRQFQGVVIKTIGDSVMAEFPEPLLAVRAAVEI…
A0A7J8FMZ6 8-151 YVRDFEADDTCLAHCWVVVRLDGRNFHRFSEKHNFAKPNDSRALHLMTKCAQTVMEELEDIVIAYGQSDEYSFVFKRKSNWFKRRAS…
A0A3M1BRV7 614-811 None
A0A538QEA6 234-391 None
A0A538PYS9 120-290 None
A0A1G0ZIW0 671-881 None
A0A2P7B837 1-153 None
A0A522XAN8 606-780 None
A0A100HM64 3-130 None
A0A840RP02 245-429 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.