DPCstruct | MC38026

Metacluster Properties and Pfam Annotations

Number of structural domains370
Mean domain length (aa)224 ± 48 aa
Standard deviation of domain lengths47.88
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score77.67
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)17.84
Pfam Score87.65
Assigned Pfam label(s) PF10683- CL0687- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1C7MWC5 15-255 DKFQEELPVDGMFSLSVGEKSLWGTKVEVVAAAYTTPGPSADDEDEDCFAESVEVNSFKANNNNKRNGSSRRYDENGVLSMSCARHD…
A0A5C2RNJ4 6-152 AVSGVFVCLCWHGHILIMCDMIRSSELMKYALTLINKLLQVYGSDILVGYDIGCEFSKTLSNSSLGAVVQEQRIKCIVLAFHGHSHN…
A0A165YB41 272-537 None
A0A284R2F6 61-363 None
A0A0C9UCM2 23-180 None
A0A146HLT1 52-259 None
Q5KN53 918-1077 None
A0A2H3BRS7 304-529 None
A0A4S8M9G4 81-353 None
A0A067C829 20-216 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.