DPCstruct | MC37866

Metacluster Properties and Pfam Annotations

Number of structural domains126
Mean domain length (aa)202 ± 30 aa
Standard deviation of domain lengths29.83
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score86.03
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)14.87
Pfam Score42.86
Assigned Pfam label(s) PF18941- PF07285

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A356TME2 98-301 CEASLAGYVRQVTRTLRDRAAQASAPADAGQLLPVLRPTGYAQMVHERTGVAGVPFGAELVALVVLDSPTTAQPVDTDLLARLGLSS…
A0A512M214 18-194 EKPKLETLLMLPEPKEMRTERSVVPEGAQATVLTPAREIADVPGIEVYPKEDFAKLGLSPETFAERSKKTAEKLLTEIKPDVIKGAD…
A0A1H9FCD8 360-560 None
A0A2T0KID5 62-247 None
A0A810KTF2 128-354 None
A0A3S0ZRK1 342-544 None
A0A2S8H7U9 65-276 None
A0A847F7P4 195-372 None
R9MEK0 9-172 None
A0A4Q7YMW3 337-539 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.