DPCstruct | MC3781

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)264 ± 19 aa
Standard deviation of domain lengths18.81
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score68.44
Mean fraction of residues predicted as intrinsically disordered0.86
Mean length-normalized TM-Score0.21
Mean intra-cluster local Distance Difference Test score0.73
Mean intra-cluster sequence similarity (%)29.56
Pfam Score87.50
Assigned Pfam label(s) PF10453- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4S2MWK8 145-415 LKTPPQSSYGQYAYPLDTCTGDTQPPNKKQRLGRSSRPDMSEADWLALNGGKLIGTNILPPQTDEEIAGWIAERKKRFPSKATQVER…
D5G5W6 1-230 MDEETWLRLNGGKLLGTNLKPPETPEEIEEWIRERRRRFPTRERVAAKVKEEEEKKRKLAGASDASAETVRAQAPATSRQALATAQQ…
A0A2N6NGJ7 205-469 None
A0A4T0VNR4 68-316 None
A0A197JYV0 245-527 None
A0A0M8MTQ1 26-278 None
H0ERN7 85-372 None
U4LSD9 1-232 None
A0A1Y2DSK0 282-548 None
M7T0F3 227-499 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.