DPCstruct | MC378

Metacluster Properties and Pfam Annotations

Number of structural domains13
Mean domain length (aa)365 ± 39 aa
Standard deviation of domain lengths39.15
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score82.26
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)18.98
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2H6ICC0 249-615 YATLLSQPKIKTNIIWEGSGGIKNYPSWTASRKADLNNSILRLEKGEPQALSAPPALLSGGYISASDAWQIYIAHIAQSLWTEVHGA…
A0A497XCK1 28-377 PPSVSCWLRAHPNVANAIKWQVMFQVSAYDIPETAKRAWPNWSSQERARLDTAFDEAWEWMQAQSGTFSASAEGLPYPPVNVRDTTN…
A0A2D6R7A5 2-291 None
A0A1F9B9U6 122-472 None
A0A7J4QC21 132-518 None
A0A6B1AKM8 214-600 None
A0A0Q4GLW5 27-359 None
A0A534TZ06 175-511 None
A0A7Y1Y4Y3 50-444 None
A0A7T9HPM8 68-510 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.