DPCstruct | MC37793

Metacluster Properties and Pfam Annotations

Number of structural domains63
Mean domain length (aa)104 ± 17 aa
Standard deviation of domain lengths17.18
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score87.80
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)45.15
Pfam Score93.37
Assigned Pfam label(s) CL0052- CL0036

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6D0M6I8 4-117 AGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVGPGELMVIDTRGGRILHSAETDHDLKSRHPYK…
X8BHX7 149-243 DGPASMTFTDGTVVGAVLDRNGLRPSRIWVTDDGLVVMASEAGVLDLDPSKVVRRMRLQPGRMFLVDTAQGRIVDDEEIKAELAAQH…
W4QIA8 355-447 None
A0A2R7RNQ8 238-325 None
A0A397EI07 63-173 None
A0A212DLH0 110-234 None
A0A182TIG5 265-373 None
A0A0Q9XCL6 412-531 None
A0A5K4EM75 111-195 None
A0A5E4PR16 293-389 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.