DPCstruct | MC37778

Metacluster Properties and Pfam Annotations

Number of structural domains43
Mean domain length (aa)179 ± 23 aa
Standard deviation of domain lengths22.54
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score79.53
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.39
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)13.77
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C5LK22 1-211 MDGGATSARRPGLDWRLVAGINLLLGALLLFMDCTDYSWANNAADALFGPLVAIVAIVSMCGARWRATWRRWRIRIASLPSLIEGGM…
A0A1M5THH7 5-180 KKIILRIYFIICALFVLDCLLYYFKEISLHGYYSDVVLSWLWLISSFVIIIVFWKKLLAKLFLTALLVTFAMSIIAMMLPFYTLLLS…
A0A2G1VST8 2-149 None
A0A163ACF6 12-162 None
A0A3S2XI59 1-177 None
A0A4R3L7Y8 1-170 None
A0A3E0VQV4 24-185 None
A0A554A3K2 1-177 None
A0A2P1WH11 48-221 None
A0A7X6S9I7 39-219 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.