DPCstruct | MC3776

Metacluster Properties and Pfam Annotations

Number of structural domains119
Mean domain length (aa)69 ± 7 aa
Standard deviation of domain lengths7.01
Length coefficient of variation0.10
Mean AlphaFold2 pLDDT confidence score84.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)52.87
Pfam Score97.50
Assigned Pfam label(s) CL0067- PF04998

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7Y2X4A2 120-194 QGITRASLQTKSFISAASFQETTKVLNEAAVSGKVDTLEGLKENVIVGHKIPAGTGMRDYEDIIVGSKEEYDEIM
A0A7V4A1D0 135-220 KPLLMGVTKSALSTKSWLSAASFQNTTHVLTEAAIAGKKDELIGLKENVILGRLIPAGTGNDFVRFTQVVDRKTLKAIEEARKEAV
A0A3B0P056 128-192 None
A0A6B1F5J4 447-523 None
A0A7Y7CRY0 355-424 None
A0A830CAL8 9-70 None
A0A7V3AU47 1-66 None
A0A7R9FUS0 100-167 None
A0A1V5HR83 61-127 None
A0A0G1K9N5 641-712 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.