DPCstruct | MC3775

Metacluster Properties and Pfam Annotations

Number of structural domains20
Mean domain length (aa)140 ± 19 aa
Standard deviation of domain lengths18.52
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.80
Mean fraction of residues predicted as intrinsically disordered0.55
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)30.98
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W8ENG3 1-103 MRSNGRSILASTLPPNDLNLHPGERLTMVCPDCRTWRVIRRGMIWPHRADDGVTRCPGSGTRLVVDLTSVEWRSAMVVAVRQAATRR…
A0A3M2MDM9 1-153 MKHNGRPPISVSALPLNHVNLRRPDGERPDGERTMIVCPDCGTWVSLKRHLVLPHRISRYTDKQIRNFALGRRPAPAARRQERCPGS…
A0A7J0D6Q2 27-173 None
A0A7X0FUS1 1-117 None
A0A286E822 21-177 None
A0A2A2D5U0 1-151 None
H2KA64 1-142 None
A0A117QWT6 14-160 None
A0A401YYP9 20-185 None
A0A345XSS6 7-140 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.