DPCstruct | MC37694

Metacluster Properties and Pfam Annotations

Number of structural domains133
Mean domain length (aa)186 ± 35 aa
Standard deviation of domain lengths34.67
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score85.92
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.66
Mean intra-cluster local Distance Difference Test score0.66
Mean intra-cluster sequence similarity (%)25.70
Pfam Score85.34
Assigned Pfam label(s) CL0123- PF08033- PF04810- CL0128

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183J790 11-183 EEIDGVRFDWNVWPHSRIEAQRLVVPIGCLFTPLKERPQDAAQPPPLNYDPVLCSRPTCKAVLNPYAQVDYRNKQWVCPLCFQRNPF…
A0A2G9RY05 2-148 AKQSQVPLAAVIKPLATLPSDEALPCVVDHGETGPIRCNRCKAYMCPSMQFIEGGRRFQCCFCSCVTEVPPHYFQHLDHTGKRVDCY…
A0A0D2NIF7 172-389 None
A0A0V0R1R4 115-344 None
A0A7J0FVK2 3-201 None
A0A5B7DRB5 603-746 None
A0A7R9PUE4 425-630 None
A0A7J9KRU9 3-194 None
A0A7R9A1X6 243-406 None
A0A6V7PFP6 87-240 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.