DPCstruct | MC3768

Metacluster Properties and Pfam Annotations

Number of structural domains17
Mean domain length (aa)115 ± 15 aa
Standard deviation of domain lengths15.33
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score87.51
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)22.76
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
E1VP18 59-172 KLVRYVSKDGMAHAVYLASFTPGHEDKATHVLVGLGKWGEDAPPSERTAFAVKIWDNDDQWAVSVLDKDDSPWGSVEFLGKVLDRDE…
A0A1F9KIG2 16-121 VHRENQTEAAYFVHWSLGKVAEKGAHIDLILGPWGEGTERADRYAVSLEFRQGFGVRIIDASIRNIARHSLVGRGLPREDVIMTPLA…
A0A2A4ZCD8 2-93 None
A0A699GFB8 1153-1262 None
A0A0F5PW86 2-113 None
A0A3B1B7H7 12-134 None
A0A7Y4ZKY0 12-133 None
A0A6G6Y8H2 3-96 None
A0A323UC43 37-150 None
A0A3B7M5J1 1-135 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.