DPCstruct | MC37675

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)229 ± 51 aa
Standard deviation of domain lengths51.24
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.65
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.30
Pfam Score91.20
Assigned Pfam label(s) CL0459- PF11411- PF10283- CL0219- PF03167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Y1W5J3 184-534 None
A0A6A2XN59 2-138 None
A0A7S1KSN6 174-445 None
A0A1W0E7P4 231-437 None
B4IG58 123-364 None
S4R8J9 21-238 None
A0A5E4PY26 244-431 None
R7QQX4 263-474 None
A0A3M9XVW1 4-207 None
A0A2P8Z0P2 8-199 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.