DPCstruct | MC37675

Metacluster Properties and Pfam Annotations

Number of structural domains743
Mean domain length (aa)229 ± 51 aa
Standard deviation of domain lengths51.24
Length coefficient of variation0.22
Mean AlphaFold2 pLDDT confidence score76.65
Mean fraction of residues predicted as intrinsically disordered0.28
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)14.30
Pfam Score91.20
Assigned Pfam label(s) CL0459- PF11411- PF10283- CL0219- PF03167

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A146HHB5 11-192 LAFKFFIQKDLPETLQAELCETIASLGGRVEIKVPRAGFILINPNTPEEERLRLCWMSPDRPERYFVPYTFVDACKVANMLLKQIFL…
A0A6L5CQB4 41-267 KLGQEENLESSCLLETMNDSGATYNSSTLAFSEPKCNKKLSITKGNLVLTSLSQEEMTFVEEVTNKLGSYAIVNEVDATVTHIVCGL…
A0A2W1BR07 3-237 None
A0A1Z5ST25 10-301 None
A0A2W1BSD6 322-544 None
W6Y0J9 2-226 None
A0A7S2UTY0 37-190 None
B5VL86 4-220 None
A0A0S4KQZ9 741-1067 None
R1CRK5 135-343 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.