DPCstruct | MC37668

Metacluster Properties and Pfam Annotations

Number of structural domains134
Mean domain length (aa)175 ± 33 aa
Standard deviation of domain lengths33.02
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score88.64
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.79
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)38.48
Pfam Score99.21
Assigned Pfam label(s) PF00925- PF00926

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6L5C5U8 11-201 AIKDIRKGKCIILVDDEDRENEGDLVIAADKVTPQAINFMAKHARGLICLALTPERCEELQLPPQAIENTATFGTAFTVSVDARKGI…
A0A080KN16 2-153 ALTIRYGSGIVCLCMPQSFCDKLELPMMVTNNTSKNHTAFTITIEAAKGVTTGVSAADRVTTVKAAVADNAKPSDLNHPGHVFPLVA…
G4MAL5 5-161 None
A0A6L5EYZ1 55-161 None
A0A1V2LQW4 640-827 None
A0A1Q9C9X7 740-867 None
A0A6A7G9R6 127-320 None
A0A177WMA1 288-493 None
A0A7C7XCG8 15-197 None
A0A2T6ZSL8 10-218 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.