DPCstruct | MC37614

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)112 ± 15 aa
Standard deviation of domain lengths14.84
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score77.44
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.80
Mean intra-cluster local Distance Difference Test score0.78
Mean intra-cluster sequence similarity (%)32.47
Pfam Score96.67
Assigned Pfam label(s) CL0521- CL0051

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2J8WD90 6-118 LSFSEREGCRNLLGLLDNDEIMALCDTVTNRLVQPQDRQDAVHAILVYSQSAEELLRRRKVHREVIFKYLATQGIIIPPATEKHNLI…
A0A672TAI7 5-101 MSKLSMKEQSGCRKLLRLLPLDDLFALKDTVTNRLIAVESTQEAIEAIISYSQDAEELLKRKKVHRDVIFKYLAKEGVAMPPNSDKQ…
A0A7R8D1J2 2-116 None
A0A815FXA9 1-111 None
A0A6P7U4L9 3-121 None
A0A815LE10 652-769 None
A0A821TJA3 1-82 None
T1FJS2 3-103 None
A0A4Y2SZJ7 59-160 None
T1GCY3 2-113 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.