DPCstruct | MC376

Metacluster Properties and Pfam Annotations

Number of structural domains35
Mean domain length (aa)124 ± 16 aa
Standard deviation of domain lengths15.61
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score82.72
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.56
Mean intra-cluster sequence similarity (%)19.72
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V9Q6D6 31-154 PKSAAHSLSRLCSREGLPNVDGSWRPTKYDIELLESRLADISRLRSKGALKSIQISQPGRYYRQYIAVVVGGHRLIYVNAFSHRPTS…
A0A523U6A5 252-380 IKTDKSEGVIFPKSAAESLVAGQLKSVKKSWTPKEKDIKKLEAKLEQYLMGNPPEKAPKLHEKLSEYKRQYTGITVEKKKRIYVNLF…
A0A7Y8THX8 27-158 None
A0A501Q2D3 125-249 None
A0A1V5H5V4 206-333 None
A0A7T7ZXR7 3-143 None
A0A2G2KWQ2 29-125 None
A0A1Q3WKP3 86-205 None
A0A4Q8S4B3 7-124 None
A0A661P5K2 99-244 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.